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A genetically encoded tool for manipulation of NADP(+)/NADPH in living cells

NADH and NADPH are redox coenzymes broadly required for energy metabolism, biosynthesis and detoxification. Despite detailed knowledge of specific enzymes and pathways that utilize these coenzymes, a holistic understanding of the regulation and compartmentalization of NADH and NADPH-dependent pathwa...

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Detalles Bibliográficos
Autores principales: Cracan, Valentin, Titov, Denis V., Shen, Hongying, Grabarek, Zenon, Mootha, Vamsi K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605434/
https://www.ncbi.nlm.nih.gov/pubmed/28805804
http://dx.doi.org/10.1038/nchembio.2454