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A genetically encoded tool for manipulation of NADP(+)/NADPH in living cells
NADH and NADPH are redox coenzymes broadly required for energy metabolism, biosynthesis and detoxification. Despite detailed knowledge of specific enzymes and pathways that utilize these coenzymes, a holistic understanding of the regulation and compartmentalization of NADH and NADPH-dependent pathwa...
Autores principales: | Cracan, Valentin, Titov, Denis V., Shen, Hongying, Grabarek, Zenon, Mootha, Vamsi K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605434/ https://www.ncbi.nlm.nih.gov/pubmed/28805804 http://dx.doi.org/10.1038/nchembio.2454 |
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