Stochastic priming and spatial cues orchestrate heterogeneous clonal contribution to mouse pancreas organogenesis

Spatiotemporal balancing of cellular proliferation and differentiation is crucial for postnatal tissue homoeostasis and organogenesis. During embryonic development, pancreatic progenitors simultaneously proliferate and differentiate into the endocrine, ductal and acinar lineages. Using in vivo clona...

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Detalles Bibliográficos
Autores principales: Larsen, Hjalte List, Martín-Coll, Laura, Nielsen, Alexander Valentin, Wright, Christopher V. E., Trusina, Ala, Kim, Yung Hae, Grapin-Botton, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605525/
https://www.ncbi.nlm.nih.gov/pubmed/28928395
http://dx.doi.org/10.1038/s41467-017-00258-4

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