Upregulation of CISD2 augments ROS homeostasis and contributes to tumorigenesis and poor prognosis of lung adenocarcinoma

CISD2 is a redox-sensitive gene critical for normal development and mitochondrial integrity. CISD2 was known to have aberrant expression in several types of human cancers. However, its relation with lung cancer is still not clear. In this study we found CISD2 mRNA was significantly upregulated in lu...

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Detalles Bibliográficos
Autores principales: Li, Shih-Miao, Chen, Chung-Hsing, Chen, Ya-Wen, Yen, Yi-Chen, Fang, Wen-Tsen, Tsai, Fang-Yu, Chang, Junn-Liang, Shen, Ying-Ying, Huang, Shiu-Feng, Chuu, Chih-Pin, Chang, I-Shou, Hsiung, Chao A., Jiang, Shih Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605537/
https://www.ncbi.nlm.nih.gov/pubmed/28928421
http://dx.doi.org/10.1038/s41598-017-12131-x

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