Tumor induces muscle wasting in mice through releasing extracellular Hsp70 and Hsp90

Cachexia, characterized by muscle wasting, is a major contributor to cancer-related mortality. However, the key cachexins that mediate cancer-induced muscle wasting remain elusive. Here, we show that tumor-released extracellular Hsp70 and Hsp90 are responsible for tumor’s capacity to induce muscle w...

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Detalles Bibliográficos
Autores principales: Zhang, Guohua, Liu, Zhelong, Ding, Hui, Zhou, Yong, Doan, Hoang Anh, Sin, Ka Wai Thomas, Zhu, Zhiren J., Flores, Rene, Wen, Yefei, Gong, Xing, Liu, Qingyun, Li, Yi-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605540/
https://www.ncbi.nlm.nih.gov/pubmed/28928431
http://dx.doi.org/10.1038/s41467-017-00726-x

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