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Modifications and Trafficking of APP in the Pathogenesis of Alzheimer’s Disease

Alzheimer’s disease (AD), the most common neurodegenerative disorder, is the leading cause of dementia. Neuritic plaque, one of the major characteristics of AD neuropathology, mainly consists of amyloid β (Aβ) protein. Aβ is derived from amyloid precursor protein (APP) by sequential cleavages of β-...

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Detalles Bibliográficos
Autores principales:	Wang, Xin, Zhou, Xuan, Li, Gongying, Zhang, Yun, Wu, Yili, Song, Weihong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605621/ https://www.ncbi.nlm.nih.gov/pubmed/28966576 http://dx.doi.org/10.3389/fnmol.2017.00294

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