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Detection of clinically relevant copy number alterations in oral cancer progression using multiplexed droplet digital PCR

Copy number alterations (CNAs), a common genomic event during carcinogenesis, are known to affect a large fraction of the genome. Common recurrent gains or losses of specific chromosomal regions occur at frequencies that they may be considered distinctive features of tumoral cells. Here we introduce...

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Detalles Bibliográficos
Autores principales: Hughesman, Curtis B., Lu, X. J. David, Liu, Kelly Y. P., Zhu, Yuqi, Towle, Rebecca M., Haynes, Charles, Poh, Catherine F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605662/
https://www.ncbi.nlm.nih.gov/pubmed/28928368
http://dx.doi.org/10.1038/s41598-017-11201-4