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Detection of clinically relevant copy number alterations in oral cancer progression using multiplexed droplet digital PCR
Copy number alterations (CNAs), a common genomic event during carcinogenesis, are known to affect a large fraction of the genome. Common recurrent gains or losses of specific chromosomal regions occur at frequencies that they may be considered distinctive features of tumoral cells. Here we introduce...
Autores principales: | Hughesman, Curtis B., Lu, X. J. David, Liu, Kelly Y. P., Zhu, Yuqi, Towle, Rebecca M., Haynes, Charles, Poh, Catherine F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605662/ https://www.ncbi.nlm.nih.gov/pubmed/28928368 http://dx.doi.org/10.1038/s41598-017-11201-4 |
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