Dimerization regulates both deaminase-dependent and deaminase-independent HIV-1 restriction by APOBEC3G

APOBEC3G (A3G) is a human enzyme that inhibits human immunodeficiency virus type 1 (HIV-1) infectivity, in the absence of the viral infectivity factor Vif, through deoxycytidine deamination and a deamination-independent mechanism. A3G converts from a fast to a slow binding state through oligomerizat...

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Detalles Bibliográficos
Autores principales: Morse, Michael, Huo, Ran, Feng, Yuqing, Rouzina, Ioulia, Chelico, Linda, Williams, Mark C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605669/
https://www.ncbi.nlm.nih.gov/pubmed/28928403
http://dx.doi.org/10.1038/s41467-017-00501-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605669/
https://www.ncbi.nlm.nih.gov/pubmed/28928403
http://dx.doi.org/10.1038/s41467-017-00501-y

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