Novel MYC-driven medulloblastoma models from multiple embryonic cerebellar cells

Group3 medulloblastoma (MB(G3)) that predominantly occur in young children are usually associated with MYC amplification and/or overexpression, frequent metastasis and a dismal prognosis. Physiologically relevant MB(G3) models are currently lacking, making inferences related to their cellular origin...

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Detalles Bibliográficos
Autores principales: Kawauchi, D, Ogg, R J, Liu, L, Shih, D J H, Finkelstein, D, Murphy, B L, Rehg, J E, Korshunov, A, Calabrese, C, Zindy, F, Phoenix, T, Kawaguchi, Y, Gronych, J, Gilbertson, R J, Lichter, P, Gajjar, A, Kool, M, Northcott, P A, Pfister, S M, Roussel, M F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605674/
https://www.ncbi.nlm.nih.gov/pubmed/28504719
http://dx.doi.org/10.1038/onc.2017.110

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