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Enabling stop codon read-through translation in bacteria as a probe for amyloid aggregation
Amyloid aggregation of the eukaryotic translation terminator eRF3/Sup35p, the [PSI (+)] prion, empowers yeast ribosomes to read-through UGA stop codons. No similar functional prion, skipping a stop codon, has been found in Escherichia coli, a fact possibly due to the efficient back-up systems found...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605706/ https://www.ncbi.nlm.nih.gov/pubmed/28928456 http://dx.doi.org/10.1038/s41598-017-12174-0 |