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Systematic single-cell analysis provides new insights into heterogeneity and plasticity of the pancreas
BACKGROUND: Diabetes mellitus is characterized by loss or dysfunction of insulin-producing β-cells in the pancreas, resulting in failure of blood glucose regulation and devastating secondary complications. Thus, β-cells are currently the prime target for cell-replacement and regenerative therapy. Tr...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605721/ https://www.ncbi.nlm.nih.gov/pubmed/28951822 http://dx.doi.org/10.1016/j.molmet.2017.06.021 |