Cargando…
Interrogating islets in health and disease with single-cell technologies
BACKGROUND: Blood glucose levels are tightly controlled by the coordinated actions of hormone-producing endocrine cells that reside in pancreatic islets. Islet cell malfunction underlies diabetes development and progression. Due to the cellular heterogeneity within islets, it has been challenging to...
Autores principales: | Carrano, Andrea C., Mulas, Francesca, Zeng, Chun, Sander, Maike |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605723/ https://www.ncbi.nlm.nih.gov/pubmed/28951823 http://dx.doi.org/10.1016/j.molmet.2017.04.012 |
Ejemplares similares
-
Human stem cell models: lessons for pancreatic development and disease
por: Gaertner, Bjoern, et al.
Publicado: (2019) -
Using single-nucleus RNA-sequencing to interrogate transcriptomic profiles of archived human pancreatic islets
por: Basile, Giorgio, et al.
Publicado: (2021) -
A Network of microRNAs Acts to Promote Cell Cycle Exit and Differentiation of Human Pancreatic Endocrine Cells
por: Jin, Wen, et al.
Publicado: (2019) -
Interrogating the promise of technology in epilepsy care: systematic, hermeneutic review
por: Papoutsi, Chrysanthi, et al.
Publicado: (2021) -
Single-cell RNA-seq methods to interrogate virus-host interactions
por: Ratnasiri, Kalani, et al.
Publicado: (2022)