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The dynamic plasticity of insulin production in β-cells

BACKGROUND: Although the insulin-producing pancreatic β-cells are quite capable of adapting to both acute and chronic changes in metabolic demand, persistently high demand for insulin will ultimately lead to their progressive dysfunction and eventual loss. Recent and historical studies highlight the...

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Detalles Bibliográficos
Autores principales: Boland, Brandon B., Rhodes, Christopher J., Grimsby, Joseph S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605729/
https://www.ncbi.nlm.nih.gov/pubmed/28951821
http://dx.doi.org/10.1016/j.molmet.2017.04.010