Human beta cell mass and function in diabetes: Recent advances in knowledge and technologies to understand disease pathogenesis

BACKGROUND: Plasma insulin levels are predominantly the product of the morphological mass of insulin producing beta cells in the pancreatic islets of Langerhans and the functional status of each of these beta cells. Thus, deficiency in either beta cell mass or function, or both, can lead to insuffic...

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Detalles Bibliográficos
Autores principales: Chen, Chunguang, Cohrs, Christian M., Stertmann, Julia, Bozsak, Robert, Speier, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605733/
https://www.ncbi.nlm.nih.gov/pubmed/28951820
http://dx.doi.org/10.1016/j.molmet.2017.06.019

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