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Changes in T Cell and Dendritic Cell Phenotype from Mid to Late Pregnancy Are Indicative of a Shift from Immune Tolerance to Immune Activation

During pregnancy, the mother allows the immunologically distinct fetoplacental unit to develop and grow. Opinions are divided as to whether this represents a state of fetal-specific tolerance or of a generalized suppression of the maternal immune system. We hypothesized that antigen-specific T cell...

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Detalles Bibliográficos
Autores principales: Shah, Nishel Mohan, Herasimtschuk, Anna A., Boasso, Adriano, Benlahrech, Adel, Fuchs, Dietmar, Imami, Nesrina, Johnson, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605754/
https://www.ncbi.nlm.nih.gov/pubmed/28966619
http://dx.doi.org/10.3389/fimmu.2017.01138