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Exercise-induced irisin in bone and systemic irisin administration reveal new regulatory mechanisms of bone metabolism

Irisin is a polypeptide hormone derived from the proteolytic cleavage of fibronectin-type III domain-containing 5 (FNDC5) protein. Once released to circulation upon exercise or cold exposure, irisin stimulates browning of white adipose tissue (WAT) and uncoupling protein 1 (UCP1) expression, leading...

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Detalles Bibliográficos
Autores principales:	Zhang, Jin, Valverde, Paloma, Zhu, Xiaofang, Murray, Dana, Wu, Yuwei, Yu, Liming, Jiang, Hua, Dard, Michel M, Huang, Jin, Xu, Zhiwei, Tu, Qisheng, Chen, Jake
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605767/ https://www.ncbi.nlm.nih.gov/pubmed/28944087 http://dx.doi.org/10.1038/boneres.2016.56

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