Loss of the vitamin D receptor in human breast and prostate cancers strongly induces cell apoptosis through downregulation of Wnt/β-catenin signaling

Vitamin D co-regulates cell proliferation, differentiation and apoptosis in numerous tissues, including cancers. The known anti-proliferative and pro-apoptotic actions of the active metabolite of vitamin D, 1,25-dihydroxy-vitamin D [1,25(OH)(2)D] are mediated through binding to the vitamin D recepto...

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Detalles Bibliográficos
Autores principales: Zheng, Yu, Trivedi, Trupti, Lin, Ruby CY, Fong-Yee, Colette, Nolte, Rick, Manibo, Jeline, Chen, Yunzhao, Hossain, Musharraf, Horas, Konstantin, Dunstan, Colin, Zhou, Hong, Seibel, Markus J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605769/
https://www.ncbi.nlm.nih.gov/pubmed/28944088
http://dx.doi.org/10.1038/boneres.2017.23

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