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Monitoring thioredoxin redox with a genetically encoded red fluorescent biosensor
Thioredoxin (Trx) is one of the two major thiol antioxidants playing essential roles in redox homeostasis and signaling. Despite the importance, there is a lack of method in monitoring Trx redox dynamics in live cells, hindering a better understanding of physiological and pathological roles of the T...
Autores principales: | Fan, Yichong, Makar, Merna, Wang, Michael X., Ai, Hui-wang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605834/ https://www.ncbi.nlm.nih.gov/pubmed/28671680 http://dx.doi.org/10.1038/nchembio.2417 |
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