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Combination of Deep Recurrent Neural Networks and Conditional Random Fields for Extracting Adverse Drug Reactions from User Reviews

Adverse drug reactions (ADRs) are an essential part of the analysis of drug use, measuring drug use benefits, and making policy decisions. Traditional channels for identifying ADRs are reliable but very slow and only produce a small amount of data. Text reviews, either on specialized web sites or in...

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Detalles Bibliográficos
Autores principales: Tutubalina, Elena, Nikolenko, Sergey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605929/
https://www.ncbi.nlm.nih.gov/pubmed/29177027
http://dx.doi.org/10.1155/2017/9451342
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author Tutubalina, Elena
Nikolenko, Sergey
author_facet Tutubalina, Elena
Nikolenko, Sergey
author_sort Tutubalina, Elena
collection PubMed
description Adverse drug reactions (ADRs) are an essential part of the analysis of drug use, measuring drug use benefits, and making policy decisions. Traditional channels for identifying ADRs are reliable but very slow and only produce a small amount of data. Text reviews, either on specialized web sites or in general-purpose social networks, may lead to a data source of unprecedented size, but identifying ADRs in free-form text is a challenging natural language processing problem. In this work, we propose a novel model for this problem, uniting recurrent neural architectures and conditional random fields. We evaluate our model with a comprehensive experimental study, showing improvements over state-of-the-art methods of ADR extraction.
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spelling pubmed-56059292017-11-26 Combination of Deep Recurrent Neural Networks and Conditional Random Fields for Extracting Adverse Drug Reactions from User Reviews Tutubalina, Elena Nikolenko, Sergey J Healthc Eng Research Article Adverse drug reactions (ADRs) are an essential part of the analysis of drug use, measuring drug use benefits, and making policy decisions. Traditional channels for identifying ADRs are reliable but very slow and only produce a small amount of data. Text reviews, either on specialized web sites or in general-purpose social networks, may lead to a data source of unprecedented size, but identifying ADRs in free-form text is a challenging natural language processing problem. In this work, we propose a novel model for this problem, uniting recurrent neural architectures and conditional random fields. We evaluate our model with a comprehensive experimental study, showing improvements over state-of-the-art methods of ADR extraction. Hindawi 2017 2017-09-05 /pmc/articles/PMC5605929/ /pubmed/29177027 http://dx.doi.org/10.1155/2017/9451342 Text en Copyright © 2017 Elena Tutubalina and Sergey Nikolenko. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Tutubalina, Elena
Nikolenko, Sergey
Combination of Deep Recurrent Neural Networks and Conditional Random Fields for Extracting Adverse Drug Reactions from User Reviews
title Combination of Deep Recurrent Neural Networks and Conditional Random Fields for Extracting Adverse Drug Reactions from User Reviews
title_full Combination of Deep Recurrent Neural Networks and Conditional Random Fields for Extracting Adverse Drug Reactions from User Reviews
title_fullStr Combination of Deep Recurrent Neural Networks and Conditional Random Fields for Extracting Adverse Drug Reactions from User Reviews
title_full_unstemmed Combination of Deep Recurrent Neural Networks and Conditional Random Fields for Extracting Adverse Drug Reactions from User Reviews
title_short Combination of Deep Recurrent Neural Networks and Conditional Random Fields for Extracting Adverse Drug Reactions from User Reviews
title_sort combination of deep recurrent neural networks and conditional random fields for extracting adverse drug reactions from user reviews
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605929/
https://www.ncbi.nlm.nih.gov/pubmed/29177027
http://dx.doi.org/10.1155/2017/9451342
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