Combining Comprehensive Analysis of Off-Site Lambda Phage Integration with a CRISPR-Based Means of Characterizing Downstream Physiology

During its lysogenic life cycle, the phage genome is integrated into the host chromosome by site-specific recombination. In this report, we analyze lambda phage integration into noncanonical sites using next-generation sequencing and show that it generates significant genetic diversity by targeting...

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Detalles Bibliográficos
Autores principales: Tanouchi, Yu, Covert, Markus W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Observation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605937/
https://www.ncbi.nlm.nih.gov/pubmed/28928209
http://dx.doi.org/10.1128/mBio.01038-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605937/
https://www.ncbi.nlm.nih.gov/pubmed/28928209
http://dx.doi.org/10.1128/mBio.01038-17

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