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The CRISPR Spacer Space Is Dominated by Sequences from Species-Specific Mobilomes

Clustered regularly interspaced short palindromic repeats and CRISPR-associated protein (CRISPR-Cas) systems store the memory of past encounters with foreign DNA in unique spacers that are inserted between direct repeats in CRISPR arrays. For only a small fraction of the spacers, homologous sequence...

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Detalles Bibliográficos
Autores principales:	Shmakov, Sergey A., Sitnik, Vassilii, Makarova, Kira S., Wolf, Yuri I., Severinov, Konstantin V., Koonin, Eugene V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605939/ https://www.ncbi.nlm.nih.gov/pubmed/28928211 http://dx.doi.org/10.1128/mBio.01397-17

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