Genomic imprinting beyond DNA methylation: a role for maternal histones

Inheritance of DNA methylation states from gametes determines genomic imprinting in mammals. A new study shows that repressive chromatin in oocytes can also confer imprinting.

Detalles Bibliográficos
Autores principales: Hanna, Courtney W., Kelsey, Gavin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Highlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605981/
https://www.ncbi.nlm.nih.gov/pubmed/28927436
http://dx.doi.org/10.1186/s13059-017-1317-9
Descripción
Sumario:Inheritance of DNA methylation states from gametes determines genomic imprinting in mammals. A new study shows that repressive chromatin in oocytes can also confer imprinting.

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