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Genetic human prion disease modelled in PrP transgenic Drosophila

Inherited human prion diseases, such as fatal familial insomnia (FFI) and familial Creutzfeldt–Jakob disease (fCJD), are associated with autosomal dominant mutations in the human prion protein gene PRNP and accumulation of PrP(Sc), an abnormal isomer of the normal host protein PrP(C), in the brain o...

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Detalles Bibliográficos
Autores principales:	Thackray, Alana M., Cardova, Alzbeta, Wolf, Hanna, Pradl, Lydia, Vorberg, Ina, Jackson, Walker S., Bujdoso, Raymond
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2017
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5606059/ https://www.ncbi.nlm.nih.gov/pubmed/28814578 http://dx.doi.org/10.1042/BCJ20170462

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