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DNA Methylation Events as Markers for Diagnosis and Management of Acute Myeloid Leukemia and Myelodysplastic Syndrome

During the onset and progression of hematological malignancies, many changes occur in cellular epigenome, such as hypo- or hypermethylation of CpG islands in promoter regions. DNA methylation is an epigenetic modification that regulates gene expression and is a key event for tumorigenesis. The conti...

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Detalles Bibliográficos
Autores principales:	Dexheimer, Geórgia Muccillo, Alves, Jayse, Reckziegel, Laura, Lazzaretti, Gabrielle, Abujamra, Ana Lucia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2017
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5606093/ https://www.ncbi.nlm.nih.gov/pubmed/29038614 http://dx.doi.org/10.1155/2017/5472893

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