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Retinal Astrocytes and GABAergic Wide-Field Amacrine Cells Express PDGFRα: Connection to Retinal Ganglion Cell Neuroprotection by PDGF-AA

PURPOSE: Our previous experiments demonstrated that intravitreal injection of platelet-derived growth factor-AA (PDGF-AA) provides retinal ganglion cell (RGC) neuroprotection in a rodent model of glaucoma. Here we used PDGFRα-enhanced green fluorescent protein (EGFP) mice to identify retinal cells t...

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Detalles Bibliográficos
Autores principales: Takahama, Shokichi, Adetunji, Modupe O., Zhao, Tantai, Chen, Shan, Li, Wei, Tomarev, Stanislav I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5606213/
https://www.ncbi.nlm.nih.gov/pubmed/28910446
http://dx.doi.org/10.1167/iovs.21783