Cargando…

Ataxia-Telangiectasia Mutated (ATM) Protein Signaling Participates in Development of Pulmonary Arterial Hypertension in Rats

BACKGROUND: Previous studies revealed physiological and pathogenetic similarity between vascular smooth muscles cells with severe pulmonary arterial hypertension and tumors. The DNA damage response was found in both pulmonary arterial hypertension (PAH) cells and tumors. The ataxia-telangiectasia mu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hu, Fan, Liu, Caijun, Liu, Hanmin, Xie, Liang, Yu, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2017
Materias:	Animal Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5606263/ https://www.ncbi.nlm.nih.gov/pubmed/28894083 http://dx.doi.org/10.12659/MSM.906568

Ejemplares similares

Clinicopathological significance of ataxia telangiectasia-mutated (ATM) kinase and ataxia telangiectasia-mutated and Rad3-related (ATR) kinase in MYC overexpressed breast cancers
por: Savva, Constantinos, et al.
Publicado: (2019)

Identification of ATM Mutations in Korean Siblings with Ataxia-Telangiectasia
por: Huh, Hee Jae, et al.
Publicado: (2013)

Ataxia-Telangiectasia with Novel Splicing Mutations in the ATM Gene
por: Jeong, Heejeong, et al.
Publicado: (2014)

Twelve Novel Atm Mutations Identified in Chinese Ataxia Telangiectasia Patients
por: Huang, Yu, et al.
Publicado: (2013)

Association of Ataxia Telangiectasia Mutated (ATM) gene mutation/deletion with Rhabdomyosarcoma
por: Zhang, Peilin, et al.
Publicado: (2003)

Erratum to: Twelve Novel Atm Mutations Identified in Chinese Ataxia Telangiectasia Patients
por: Huang, Yu, et al.
Publicado: (2013)

Association of Ataxia Telangiectasia Mutated (ATM) Gene Mutation/Deletion with Rhabdomyosarcoma – retraction
por: Zhang, Peilin, et al.
Publicado: (2003)

Ataxia telangiectasia mutated: The potential negative regulator in platelet-derived growth factor-BB promoted proliferation of pulmonary arterial smooth muscle cells
por: Qin, Chaoyi, et al.
Publicado: (2022)

DHPLC Screening of ATM Gene in Italian Patients Affected by Ataxia-Telangiectasia: Fourteen Novel ATM Mutations
por: Magliozzi, Monia, et al.
Publicado: (2006)

Atm reactivation reverses ataxia telangiectasia phenotypes in vivo
por: Di Siena, Sara, et al.
Publicado: (2018)

Telomere length, ATM mutation status and cancer risk in Ataxia-Telangiectasia families
por: Renault, Anne-Laure, et al.
Publicado: (2017)

A Novel Splice Site Mutation of the ATM Gene Associated with Ataxia Telangiectasia
por: SAEIDI, Kolsoum, et al.
Publicado: (2018)

Development of an Immunohistochemical Assay to Detect the Ataxia-Telangiectasia Mutated (ATM) Protein in Gastric Carcinoma
por: Miller, Rachel M., et al.
Publicado: (2020)

Ataxia Telangiectasia-Mutated (ATM)Polymorphisms and Risk of Lung Cancer in a Chinese Population
por: Myneni, Ajay A., et al.
Publicado: (2017)

Quantitative Phosphoproteomics of the Ataxia Telangiectasia-Mutated (ATM) and Ataxia Telangiectasia-Mutated and Rad3-related (ATR) Dependent DNA Damage Response in Arabidopsis thaliana
por: Roitinger, Elisabeth, et al.
Publicado: (2015)

Ataxia-telangiectasia with a novel ATM gene mutation and Burkitt leukemia: A case report
por: Ye, Fanghua, et al.
Publicado: (2018)

Analysis of Clinical and Genetic Characterization of Three Ataxia–Telangiectasia Pedigrees With Novel ATM Gene Mutations
por: Huang, Peng, et al.
Publicado: (2022)

New human ATM variants are able to regain ATM functions in ataxia telangiectasia disease
por: Ricci, Anastasia, et al.
Publicado: (2022)

Severe reaction to radiotherapy provoked by hypomorphic germline mutations in ATM (ataxia–telangiectasia mutated gene)
por: Asadollahi, Reza, et al.
Publicado: (2020)

Thyroid and Breast Cancer in 2 Sisters With Monoallelic Mutations in the Ataxia Telangiectasia Mutated (ATM) Gene
por: Miasaki, Fabíola Y, et al.
Publicado: (2022)

Ten new ATM alterations in Polish patients with ataxia-telangiectasia
por: Podralska, Marta Joanna, et al.
Publicado: (2014)

ATM Kinase Dead: From Ataxia Telangiectasia Syndrome to Cancer
por: Putti, Sabrina, et al.
Publicado: (2021)

Loss of atm in Zebrafish as a Model of Ataxia–Telangiectasia Syndrome
por: Chen, Kehua, et al.
Publicado: (2022)

Mutation at Intronic Repeats of the Ataxia-Telangiectasia Mutated (ATM) Gene and ATM Protein Loss in Primary Gastric Cancer with Microsatellite Instability
por: Kim, Hee Sung, et al.
Publicado: (2013)

Ataxia-telangiectasia mutated (ATM) gene mutation in a patient with primary cutaneous marginal zone lymphoma
por: Sarver, Melissa M., et al.
Publicado: (2022)

Ataxia telangiectasia mutated (ATM) interacts with p400 ATPase for an efficient DNA damage response
por: Smith, Rebecca J., et al.
Publicado: (2016)

Effect of Reducing Ataxia-Telangiectasia Mutated (ATM) in Experimental Autosomal Dominant Polycystic Kidney Disease
por: Zhang, Jennifer Q. J., et al.
Publicado: (2021)

Ibuprofen prevents progression of ataxia telangiectasia symptoms in ATM-deficient mice
por: Hui, Chin Wai, et al.
Publicado: (2018)

Two novel heterozygote mutations of ATM in a Chinese family with dystonia-dominant ataxia telangiectasia and literature review
por: Liu, Zhi-Jun, et al.
Publicado: (2023)

Ataxia-telangiectasia mutated (ATM) silencing promotes neuroblastoma progression through a MYCN independent mechanism
por: Mandriota, Stefano J., et al.
Publicado: (2015)

Identification of Two Novel Mutations in the ATM Gene from Patients with Ataxia-Telangiectasia by Whole Exome Sequencing
por: Heidari, Masoud, et al.
Publicado: (2019)

Nuclear accumulation of HDAC4 in ATM deficiency promotes neurodegeneration in ataxia-telangiectasia
por: Li, Jiali, et al.
Publicado: (2012)

Six Novel ATM Gene Variants in Sri Lankan Patients with Ataxia Telangiectasia
por: Hettiarachchi, D., et al.
Publicado: (2020)

Methylation of the ataxia telangiectasia mutated gene (ATM) promoter as a radiotherapy outcome biomarker in patients with hepatocellular carcinoma
por: Yan, Xinjian, et al.
Publicado: (2020)

ATM protein and p53-serine 15 phosphorylation in ataxia-telangiectasia (AT) patients and at heterozygotes
por: Delia, D, et al.
Publicado: (2000)

Evidence for pathogenicity of variant ATM Val1729Leu in a family with ataxia telangiectasia
por: Shalash, Ali S., et al.
Publicado: (2021)

Characteristics of Pulmonary Vascular Remodeling in a Novel Model of Shunt-Associated Pulmonary Arterial Hypertension
por: Zhang, Mingjie, et al.
Publicado: (2018)

miR-18a Impairs DNA Damage Response through Downregulation of Ataxia Telangiectasia Mutated (ATM) Kinase
por: Song, Libing, et al.
Publicado: (2011)

The prevalence of ataxia telangiectasia mutated (ATM) variants in patients with breast cancer patients: a systematic review and meta-analysis
por: Moslemi, Masoumeh, et al.
Publicado: (2021)

A novel variant in ATM gene causes ataxia telangiectasia revealed by whole-exome sequencing
por: Alonazi, Noufa A., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_dpj36uv23ht6ukks57f5jnoub2