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Tick-Borne Relapsing Fever Spirochetes in the Americas
Relapsing fever spirochetes are tick- and louse-borne pathogens that primarily afflict those in impoverished countries. Historically the pathogens have had a significant impact on public health, yet currently they are often overlooked because of the nonspecific display of disease. In this review, we...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5606572/ https://www.ncbi.nlm.nih.gov/pubmed/28959690 http://dx.doi.org/10.3390/vetsci3030016 |
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author | Lopez, Job E. Krishnavahjala, Aparna Garcia, Melissa N. Bermudez, Sergio |
author_facet | Lopez, Job E. Krishnavahjala, Aparna Garcia, Melissa N. Bermudez, Sergio |
author_sort | Lopez, Job E. |
collection | PubMed |
description | Relapsing fever spirochetes are tick- and louse-borne pathogens that primarily afflict those in impoverished countries. Historically the pathogens have had a significant impact on public health, yet currently they are often overlooked because of the nonspecific display of disease. In this review, we discuss aspects of relapsing fever (RF) spirochete pathogenesis including the: (1) clinical manifestation of disease; (2) ability to diagnose pathogen exposure; (3) the pathogen’s life cycle in the tick and mammal; and (4) ecological factors contributing to the maintenance of RF spirochetes in nature. |
format | Online Article Text |
id | pubmed-5606572 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-56065722017-09-26 Tick-Borne Relapsing Fever Spirochetes in the Americas Lopez, Job E. Krishnavahjala, Aparna Garcia, Melissa N. Bermudez, Sergio Vet Sci Review Relapsing fever spirochetes are tick- and louse-borne pathogens that primarily afflict those in impoverished countries. Historically the pathogens have had a significant impact on public health, yet currently they are often overlooked because of the nonspecific display of disease. In this review, we discuss aspects of relapsing fever (RF) spirochete pathogenesis including the: (1) clinical manifestation of disease; (2) ability to diagnose pathogen exposure; (3) the pathogen’s life cycle in the tick and mammal; and (4) ecological factors contributing to the maintenance of RF spirochetes in nature. MDPI 2016-08-15 /pmc/articles/PMC5606572/ /pubmed/28959690 http://dx.doi.org/10.3390/vetsci3030016 Text en © 2016 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Lopez, Job E. Krishnavahjala, Aparna Garcia, Melissa N. Bermudez, Sergio Tick-Borne Relapsing Fever Spirochetes in the Americas |
title | Tick-Borne Relapsing Fever Spirochetes in the Americas |
title_full | Tick-Borne Relapsing Fever Spirochetes in the Americas |
title_fullStr | Tick-Borne Relapsing Fever Spirochetes in the Americas |
title_full_unstemmed | Tick-Borne Relapsing Fever Spirochetes in the Americas |
title_short | Tick-Borne Relapsing Fever Spirochetes in the Americas |
title_sort | tick-borne relapsing fever spirochetes in the americas |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5606572/ https://www.ncbi.nlm.nih.gov/pubmed/28959690 http://dx.doi.org/10.3390/vetsci3030016 |
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