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Improvement of dyspnea after bariatric surgery is associated with increased Expiratory Reserve Volume: A prospective follow-up study of 45 patients
OBJECTIVES: To assess the effects of bariatric surgery in patients with obesity on dyspnea and to analyze the relationships between improvement of dyspnea after bariatric surgery and changes in pulmonary function, especially Expiratory Reserve Volume (ERV) which is the lung volume abnormality most f...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607210/ https://www.ncbi.nlm.nih.gov/pubmed/28931052 http://dx.doi.org/10.1371/journal.pone.0185058 |
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author | Boissière, Louis Perotin-Collard, Jeanne-Marie Bertin, Eric Gaubil, Isabelle Diaz Cives, Ana Barbe, Coralie Dury, Sandra Nardi, Julie Lebargy, François Deslée, Gaëtan Launois, Claire |
author_facet | Boissière, Louis Perotin-Collard, Jeanne-Marie Bertin, Eric Gaubil, Isabelle Diaz Cives, Ana Barbe, Coralie Dury, Sandra Nardi, Julie Lebargy, François Deslée, Gaëtan Launois, Claire |
author_sort | Boissière, Louis |
collection | PubMed |
description | OBJECTIVES: To assess the effects of bariatric surgery in patients with obesity on dyspnea and to analyze the relationships between improvement of dyspnea after bariatric surgery and changes in pulmonary function, especially Expiratory Reserve Volume (ERV) which is the lung volume abnormality most frequently associated with obesity. METHODS: Forty-five patients (5 males/40 females, mean Body Mass Index = 46.2 ± 6.8 kg/m(2)) were evaluated before and 6 to 12 months after bariatric surgery. Dyspnea was assessed by the modified Medical Research Council (mMRC) scale. Pulmonary function tests, arterial blood gases and six-minute walk test were performed. Laboratory parameters including C-Reactive Protein (CRP) were analyzed. RESULTS: Ninety percent of patients were dyspneic before surgery (mMRC scale ≥ 1) versus 59% after surgery (p<0.001). Mean mMRC score improved after bariatric surgery (1.5 ± 0.9 vs 0.7 ± 0.7, p<0.0001). Among patients with dyspnea before surgery (n = 38), a more marked increase in ERV after surgery was observed in patients with improvement of dyspnea compared to patients with no improvement of dyspnea (+0.17 ± 0.32 L vs +0.49 ± 0.35 L, p = 0.01). Multivariate analysis including age, variation of BMI, variation of CRP, variation of Total Lung Capacity and variation of ERV demonstraded that ERV was the only variable associated with improvement of the mMRc score after bariatric surgery (p = 0.04). CONCLUSION: Weight loss associated with bariatric surgery improves dyspnea in daily living. This improvement could be partly related to increased ERV. |
format | Online Article Text |
id | pubmed-5607210 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-56072102017-10-09 Improvement of dyspnea after bariatric surgery is associated with increased Expiratory Reserve Volume: A prospective follow-up study of 45 patients Boissière, Louis Perotin-Collard, Jeanne-Marie Bertin, Eric Gaubil, Isabelle Diaz Cives, Ana Barbe, Coralie Dury, Sandra Nardi, Julie Lebargy, François Deslée, Gaëtan Launois, Claire PLoS One Research Article OBJECTIVES: To assess the effects of bariatric surgery in patients with obesity on dyspnea and to analyze the relationships between improvement of dyspnea after bariatric surgery and changes in pulmonary function, especially Expiratory Reserve Volume (ERV) which is the lung volume abnormality most frequently associated with obesity. METHODS: Forty-five patients (5 males/40 females, mean Body Mass Index = 46.2 ± 6.8 kg/m(2)) were evaluated before and 6 to 12 months after bariatric surgery. Dyspnea was assessed by the modified Medical Research Council (mMRC) scale. Pulmonary function tests, arterial blood gases and six-minute walk test were performed. Laboratory parameters including C-Reactive Protein (CRP) were analyzed. RESULTS: Ninety percent of patients were dyspneic before surgery (mMRC scale ≥ 1) versus 59% after surgery (p<0.001). Mean mMRC score improved after bariatric surgery (1.5 ± 0.9 vs 0.7 ± 0.7, p<0.0001). Among patients with dyspnea before surgery (n = 38), a more marked increase in ERV after surgery was observed in patients with improvement of dyspnea compared to patients with no improvement of dyspnea (+0.17 ± 0.32 L vs +0.49 ± 0.35 L, p = 0.01). Multivariate analysis including age, variation of BMI, variation of CRP, variation of Total Lung Capacity and variation of ERV demonstraded that ERV was the only variable associated with improvement of the mMRc score after bariatric surgery (p = 0.04). CONCLUSION: Weight loss associated with bariatric surgery improves dyspnea in daily living. This improvement could be partly related to increased ERV. Public Library of Science 2017-09-20 /pmc/articles/PMC5607210/ /pubmed/28931052 http://dx.doi.org/10.1371/journal.pone.0185058 Text en © 2017 Boissière et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Boissière, Louis Perotin-Collard, Jeanne-Marie Bertin, Eric Gaubil, Isabelle Diaz Cives, Ana Barbe, Coralie Dury, Sandra Nardi, Julie Lebargy, François Deslée, Gaëtan Launois, Claire Improvement of dyspnea after bariatric surgery is associated with increased Expiratory Reserve Volume: A prospective follow-up study of 45 patients |
title | Improvement of dyspnea after bariatric surgery is associated with increased Expiratory Reserve Volume: A prospective follow-up study of 45 patients |
title_full | Improvement of dyspnea after bariatric surgery is associated with increased Expiratory Reserve Volume: A prospective follow-up study of 45 patients |
title_fullStr | Improvement of dyspnea after bariatric surgery is associated with increased Expiratory Reserve Volume: A prospective follow-up study of 45 patients |
title_full_unstemmed | Improvement of dyspnea after bariatric surgery is associated with increased Expiratory Reserve Volume: A prospective follow-up study of 45 patients |
title_short | Improvement of dyspnea after bariatric surgery is associated with increased Expiratory Reserve Volume: A prospective follow-up study of 45 patients |
title_sort | improvement of dyspnea after bariatric surgery is associated with increased expiratory reserve volume: a prospective follow-up study of 45 patients |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607210/ https://www.ncbi.nlm.nih.gov/pubmed/28931052 http://dx.doi.org/10.1371/journal.pone.0185058 |
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