Defective thymic output in WAS patients is associated with abnormal actin organization

Wiskott-Aldrich syndrome protein (WASp) is a key regulator of the actin cytoskeleton. Defective T - cell function is a major cause for immune deficiency in Wiskott-Aldrich syndrome (WAS) patients. T cells originate in the bone marrow and develop in the thymus, and then migrate to peripheral tissues....

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Detalles Bibliográficos
Autores principales: Li, Wenyan, Sun, Xiaoyu, Wang, Jinzhi, Zhao, Qin, Dai, Rongxin, Wang, Yanping, Zhou, Lina, Westerberg, Lisa, Ding, Yuan, Zhao, Xiaodong, Liu, Chaohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607224/
https://www.ncbi.nlm.nih.gov/pubmed/28931895
http://dx.doi.org/10.1038/s41598-017-12345-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607224/
https://www.ncbi.nlm.nih.gov/pubmed/28931895
http://dx.doi.org/10.1038/s41598-017-12345-z

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