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Pathogenesis of Lethal Aspiration Pneumonia in Mecp2-null Mouse Model for Rett Syndrome

Rett syndrome (RTT) is a neurodevelopmental disorder mainly caused by mutations in the gene encoding the transcriptional regulator Methyl-CpG-binding protein 2 (MeCP2), located on the X chromosome. Many RTT patients have breathing abnormalities, such as apnea and breathing irregularity, and respirat...

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Detalles Bibliográficos
Autores principales: Kida, Hiroshi, Takahashi, Tomoyuki, Nakamura, Yuki, Kinoshita, Takashi, Hara, Munetsugu, Okamoto, Masaki, Okayama, Satoko, Nakamura, Keiichiro, Kosai, Ken-ichiro, Taniwaki, Takayuki, Yamashita, Yushiro, Matsuishi, Toyojiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607245/
https://www.ncbi.nlm.nih.gov/pubmed/28931890
http://dx.doi.org/10.1038/s41598-017-12293-8