THP-1-derived macrophages render lung epithelial cells hypo-responsive to Legionella pneumophila – a systems biology study

Immune response in the lung has to protect the huge alveolar surface against pathogens while securing the delicate lung structure. Macrophages and alveolar epithelial cells constitute the first line of defense and together orchestrate the initial steps of host defense. In this study, we analysed the...

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Detalles Bibliográficos
Autores principales: Schulz, Christine, Lai, Xin, Bertrams, Wilhelm, Jung, Anna Lena, Sittka-Stark, Alexandra, Herkt, Christina Elena, Janga, Harshavadhan, Zscheppang, Katja, Stielow, Christina, Schulte, Leon, Hippenstiel, Stefan, Vera, Julio, Schmeck, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607273/
https://www.ncbi.nlm.nih.gov/pubmed/28931863
http://dx.doi.org/10.1038/s41598-017-12154-4

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