Cargando…
An iterative compound screening contest method for identifying target protein inhibitors using the tyrosine-protein kinase Yes
We propose a new iterative screening contest method to identify target protein inhibitors. After conducting a compound screening contest in 2014, we report results acquired from a contest held in 2015 in this study. Our aims were to identify target enzyme inhibitors and to benchmark a variety of com...
Autores principales: | Chiba, Shuntaro, Ishida, Takashi, Ikeda, Kazuyoshi, Mochizuki, Masahiro, Teramoto, Reiji, Taguchi, Y-h., Iwadate, Mitsuo, Umeyama, Hideaki, Ramakrishnan, Chandrasekaran, Thangakani, A. Mary, Velmurugan, D., Gromiha, M. Michael, Okuno, Tatsuya, Kato, Koya, Minami, Shintaro, Chikenji, George, Suzuki, Shogo D., Yanagisawa, Keisuke, Shin, Woong-Hee, Kihara, Daisuke, Yamamoto, Kazuki Z., Moriwaki, Yoshitaka, Yasuo, Nobuaki, Yoshino, Ryunosuke, Zozulya, Sergey, Borysko, Petro, Stavniichuk, Roman, Honma, Teruki, Hirokawa, Takatsugu, Akiyama, Yutaka, Sekijima, Masakazu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607274/ https://www.ncbi.nlm.nih.gov/pubmed/28931921 http://dx.doi.org/10.1038/s41598-017-10275-4 |
Ejemplares similares
-
Identification of potential inhibitors based on compound proposal contest: Tyrosine-protein kinase Yes as a target
por: Chiba, Shuntaro, et al.
Publicado: (2015) -
A prospective compound screening contest identified broader inhibitors for Sirtuin 1
por: Chiba, Shuntaro, et al.
Publicado: (2019) -
Distinct position-specific sequence features of hexa-peptides that form amyloid-fibrils: application to discriminate between amyloid fibril and amorphous β-aggregate forming peptide sequences
por: Thangakani, A Mary, et al.
Publicado: (2013) -
PDBparam: Online Resource for Computing Structural Parameters of Proteins
por: Nagarajan, R., et al.
Publicado: (2016) -
CPAD, Curated Protein Aggregation Database: A Repository of Manually Curated Experimental Data on Protein and Peptide Aggregation
por: Thangakani, A. Mary, et al.
Publicado: (2016)