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Mild hypothermia provides Treg stability

Regulatory T cells (Tregs) play crucial role in maintenance of peripheral tolerance. Recent clinical trials confirmed safety and efficacy of Treg treatment of deleterious immune responses. However, Tregs lose their characteristic phenotype and suppressive potential during expansion ex vivo. Therefor...

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Detalles Bibliográficos
Autores principales: Marek-Trzonkowska, Natalia, Piekarska, Karolina, Filipowicz, Natalia, Piotrowski, Arkadiusz, Gucwa, Magdalena, Vogt, Katrin, Sawitzki, Birgit, Siebert, Janusz, Trzonkowski, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607276/
https://www.ncbi.nlm.nih.gov/pubmed/28931834
http://dx.doi.org/10.1038/s41598-017-10151-1