Cargando…
Identification and characterization of a novel Sso7d scaffold-based binder against Notch1
Notch signaling has important functions in regulating cell growth and development, misregulation of which has been implicated in various cancers. Monoclonal antibodies (mAbs) targeting Notch protein activity have already moved into clinical trials. However due to the limitations associated with cost...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607287/ https://www.ncbi.nlm.nih.gov/pubmed/28931897 http://dx.doi.org/10.1038/s41598-017-12246-1 |