Longitudinal analysis of colon crypt stem cell dynamics in sulindac treated Familial Adenomatous Polyposis patients

The non-steroidal anti-inflammatory drug sulindac decreases size and number of adenomas after 4-6 months of treatment for familial adenomatous polyposis (FAP) patients. However, the underlying mechanism remains unknown. As stem cells are thought to be the tumor precursor cells, visualizing their beh...

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Detalles Bibliográficos
Autores principales: Ma, Huiying, Brosens, Lodewijk A. A., Elias, Sjoerd G., Morsink, Folkert H. M., Nijman, Isaac J., Hylind, Linda M., Montgomery, Elizabeth A., Offerhaus, G. Johan A., Giardiello, Francis M., de Leng, Wendy W. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607292/
https://www.ncbi.nlm.nih.gov/pubmed/28931879
http://dx.doi.org/10.1038/s41598-017-11865-y

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