Cargando…
Inactivation of HMGCL promotes proliferation and metastasis of nasopharyngeal carcinoma by suppressing oxidative stress
Altered metabolism is considered as a hallmark of cancer. Here we investigated expression of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) 2 lyase (HMGCL), an essential enzyme in ketogenesis, which produces ketone bodies by the breakdown of fatty acids to supply energy, in nasopharyngeal carcinoma...
Autores principales: | Luo, Wenqi, Qin, Liting, Li, Bo, Liao, Zhipeng, Liang, Jiezhen, Xiao, Xiling, Xiao, Xue, Mo, Yingxi, Huang, Guangwu, Zhang, Zhe, Zhou, Xiaoying, Li, Ping |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607293/ https://www.ncbi.nlm.nih.gov/pubmed/28931870 http://dx.doi.org/10.1038/s41598-017-11025-2 |
Ejemplares similares
-
Inactivation of 3-hydroxybutyrate dehydrogenase type 2 promotes proliferation and metastasis of nasopharyngeal carcinoma by iron retention
por: Li, Bo, et al.
Publicado: (2019) -
Epigenetic Inactivation of Acetyl-CoA Acetyltransferase 1 Promotes the Proliferation and Metastasis in Nasopharyngeal Carcinoma by Blocking Ketogenesis
por: Lu, Yunliang, et al.
Publicado: (2021) -
Downregulation of SLC27A6 by DNA Hypermethylation Promotes Proliferation but Suppresses Metastasis of Nasopharyngeal Carcinoma Through Modulating Lipid Metabolism
por: Zhong, Xuemin, et al.
Publicado: (2022) -
Epigenetic inactivation of follistatin-like 1 mediates tumor immune evasion in nasopharyngeal carcinoma
por: Zhou, Xiaoying, et al.
Publicado: (2016) -
TFPI-2 is a putative tumor suppressor gene frequently inactivated by promoter hypermethylation in nasopharyngeal carcinoma
por: Wang, Shumin, et al.
Publicado: (2010)