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Complications following vaginal mesh procedures for stress urinary incontinence: an 8 year study of 92,246 women
Complications of surgical mesh procedures have led to legal cases against manufacturers worldwide and to national inquiries about their safety. The aim of this study was to investigate the rate of adverse events of these procedures for stress urinary incontinence in England over 8 years. This was a...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607307/ https://www.ncbi.nlm.nih.gov/pubmed/28931856 http://dx.doi.org/10.1038/s41598-017-11821-w |
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author | Keltie, Kim Elneil, Sohier Monga, Ashwani Patrick, Hannah Powell, John Campbell, Bruce Sims, Andrew J. |
author_facet | Keltie, Kim Elneil, Sohier Monga, Ashwani Patrick, Hannah Powell, John Campbell, Bruce Sims, Andrew J. |
author_sort | Keltie, Kim |
collection | PubMed |
description | Complications of surgical mesh procedures have led to legal cases against manufacturers worldwide and to national inquiries about their safety. The aim of this study was to investigate the rate of adverse events of these procedures for stress urinary incontinence in England over 8 years. This was a retrospective cohort study of first-time tension-free vaginal tape (TVT), trans-obturator tape (TOT) or suprapubic sling (SS) surgical mesh procedures between April 2007 and March 2015. Cases were identified from the Hospital Episode Statistics database. Outcomes included number and type of procedures, including those potentially confounded by concomitant procedures, and frequency, nature and timing of complications. 92,246 first-time surgical mesh procedures (56,648 TVT, 34,704 TOT, 834 SS and 60 combinations) were identified, including 68,002 unconfounded procedures. Peri-procedural and 30-day complication rates in the unconfounded cohort were 2.4 [2.3–2.5]% and 1.7 [1.6–1.8]% respectively; 5.9 [5.7–6.1]% were readmitted at least once within 5 years for further mesh intervention or symptoms of complications, the highest risk being within the first 2 years. Complication rates were higher in the potentially confounded cohort. The complication rate within 5 years of the mesh procedure was 9.8 [9.6:10.0]% This evidence can inform future decision-making on this procedure. |
format | Online Article Text |
id | pubmed-5607307 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-56073072017-09-24 Complications following vaginal mesh procedures for stress urinary incontinence: an 8 year study of 92,246 women Keltie, Kim Elneil, Sohier Monga, Ashwani Patrick, Hannah Powell, John Campbell, Bruce Sims, Andrew J. Sci Rep Article Complications of surgical mesh procedures have led to legal cases against manufacturers worldwide and to national inquiries about their safety. The aim of this study was to investigate the rate of adverse events of these procedures for stress urinary incontinence in England over 8 years. This was a retrospective cohort study of first-time tension-free vaginal tape (TVT), trans-obturator tape (TOT) or suprapubic sling (SS) surgical mesh procedures between April 2007 and March 2015. Cases were identified from the Hospital Episode Statistics database. Outcomes included number and type of procedures, including those potentially confounded by concomitant procedures, and frequency, nature and timing of complications. 92,246 first-time surgical mesh procedures (56,648 TVT, 34,704 TOT, 834 SS and 60 combinations) were identified, including 68,002 unconfounded procedures. Peri-procedural and 30-day complication rates in the unconfounded cohort were 2.4 [2.3–2.5]% and 1.7 [1.6–1.8]% respectively; 5.9 [5.7–6.1]% were readmitted at least once within 5 years for further mesh intervention or symptoms of complications, the highest risk being within the first 2 years. Complication rates were higher in the potentially confounded cohort. The complication rate within 5 years of the mesh procedure was 9.8 [9.6:10.0]% This evidence can inform future decision-making on this procedure. Nature Publishing Group UK 2017-09-20 /pmc/articles/PMC5607307/ /pubmed/28931856 http://dx.doi.org/10.1038/s41598-017-11821-w Text en © The Author(s) 2017 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Keltie, Kim Elneil, Sohier Monga, Ashwani Patrick, Hannah Powell, John Campbell, Bruce Sims, Andrew J. Complications following vaginal mesh procedures for stress urinary incontinence: an 8 year study of 92,246 women |
title | Complications following vaginal mesh procedures for stress urinary incontinence: an 8 year study of 92,246 women |
title_full | Complications following vaginal mesh procedures for stress urinary incontinence: an 8 year study of 92,246 women |
title_fullStr | Complications following vaginal mesh procedures for stress urinary incontinence: an 8 year study of 92,246 women |
title_full_unstemmed | Complications following vaginal mesh procedures for stress urinary incontinence: an 8 year study of 92,246 women |
title_short | Complications following vaginal mesh procedures for stress urinary incontinence: an 8 year study of 92,246 women |
title_sort | complications following vaginal mesh procedures for stress urinary incontinence: an 8 year study of 92,246 women |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607307/ https://www.ncbi.nlm.nih.gov/pubmed/28931856 http://dx.doi.org/10.1038/s41598-017-11821-w |
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