Cargando…

Exercise training enhances in vivo clearance of endotoxin and attenuates inflammatory responses by potentiating Kupffer cell phagocytosis

The failure of Kupffer cells (KCs) to remove endotoxin is an important factor in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). In this study, the effects of exercise training on KC function were studied in terms of in vivo endotoxin clearance and inflammatory responses. Mice were al...

Descripción completa

Detalles Bibliográficos
Autores principales:	Komine, Shoichi, Akiyama, Kentaro, Warabi, Eiji, Oh, Sechang, Kuga, Keisuke, Ishige, Kazunori, Togashi, Shinji, Yanagawa, Toru, Shoda, Junichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607327/ https://www.ncbi.nlm.nih.gov/pubmed/28931917 http://dx.doi.org/10.1038/s41598-017-12358-8

Ejemplares similares

Nuclear factor (erythroid derived 2)-like 2 activation increases exercise endurance capacity via redox modulation in skeletal muscles
por: Oh, Sechang, et al.
Publicado: (2017)

Prevention of non‐alcoholic steatohepatitis by long‐term exercise via the induction of phenotypic changes in Kupffer cells of hyperphagic obese mice
por: Miura, Ikuru, et al.
Publicado: (2021)

Cytoprotective Role of Nrf2 in Electrical Pulse Stimulated C2C12 Myotube
por: Horie, Masaki, et al.
Publicado: (2015)

Macrophage specific restoration of the Nrf2 gene in whole-body knockout mice ameliorates steatohepatitis induced by lipopolysaccharide from Porphyromonas gingivalis through enhanced hepatic clearance
por: Chihara, Kanako, et al.
Publicado: (2023)

Deletion of both p62 and Nrf2 spontaneously results in the development of nonalcoholic steatohepatitis
por: Akiyama, Kentaro, et al.
Publicado: (2017)

Gender difference in development of steatohepatitis in p62/Sqstm1 and Nrf2 double-knockout mice
por: Watahiki, Takahisa, et al.
Publicado: (2020)

Effect of a sulforaphane supplement on muscle soreness and damage induced by eccentric exercise in young adults: A pilot study
por: Komine, Shoichi, et al.
Publicado: (2021)

Endotoxin and Kupffer Cell Activation in Alcoholic Liver Disease
por: Wheeler, Michael D.
Publicado: (2003)

Targeting Interleukin-4 Receptor Alpha by Hybrid Peptide for Novel Biliary Tract Cancer Therapy
por: Seto, Kahori, et al.
Publicado: (2014)

Novel roles of peroxiredoxins in inflammation, cancer and innate immunity
por: Ishii, Tetsuro, et al.
Publicado: (2012)

Effects of bile acids and endotoxin on the function and morphology of cultured hamster Kupffer cells
por: Takiguchi, Satoshi, et al.
Publicado: (1987)

Colchicine overdose impairs the capacity of Kupffer cells to clear foreign particles and endotoxins
por: Hassan, Reham, et al.
Publicado: (2022)

Editorial: Lifestyle modification strategies as first line of chronic disease management
por: Oh, Sechang, et al.
Publicado: (2023)

Negative expression of N-acetylglucosaminyltransferase V in oral squamous cell carcinoma correlates with poor prognosis
por: Seto, Kahori, et al.
Publicado: (2013)

Exercise habituation is effective for improvement of periodontal disease status: a prospective intervention study
por: Omori, Shoei, et al.
Publicado: (2018)

Chemiluminescence detection of reactive oxygen species in isolated Kupffer cells during phagocytosis of Treponema pallidum
por: Aldini, Rita, et al.
Publicado: (2004)

High-Intensity Aerobic Exercise Improves Both Hepatic Fat Content and Stiffness in Sedentary Obese Men with Nonalcoholic Fatty Liver Disease
por: Oh, Sechang, et al.
Publicado: (2017)

Trichloroethene metabolite dichloroacetyl chloride induces apoptosis and compromises phagocytosis in Kupffer Cells: Activation of inflammasome and MAPKs
por: Wang, Hui, et al.
Publicado: (2018)

Kupffer Cells and Blood Monocytes Orchestrate the Clearance of Iron–Carbohydrate Nanoparticles from Serum
por: Arsiwala, Tasneem, et al.
Publicado: (2022)

PD-1 blockade improves Kupffer cell bacterial clearance in acute liver injury
por: Triantafyllou, Evangelos, et al.
Publicado: (2021)

c-Myb Dominates TBK1-Mediated Endotoxin Tolerance in Kupffer Cells by Negatively Regulating DTX4
por: Wu, Yi-Lin, et al.
Publicado: (2023)

Dysfunctional phagocytosis capacity, granulocyte recruitment and inflammatory factor secretion of Kupffer cells in diabetes mellitus reversed by Lidocaine
por: Wang, Ruibin, et al.
Publicado: (2018)

Tumor-derived nanovesicles promote lung distribution of the therapeutic nanovector through repression of Kupffer cell-mediated phagocytosis
por: Qiu, Xiaolan, et al.
Publicado: (2019)

Progressive reduction in skeletal muscle mass to visceral fat area ratio is associated with a worsening of the hepatic conditions of non-alcoholic fatty liver disease
por: Shida, Takashi, et al.
Publicado: (2019)

Effects of zinc oxide nanoparticles on Kupffer cell phagosomal motility, bacterial clearance, and liver function
por: Watson, Christa Y, et al.
Publicado: (2015)

p62/Sqstm1 rescue in muscle retards the progression of steatohepatitis in p62/Sqstm1-null mice fed a high-fat diet
por: Miura, Ikuru, et al.
Publicado: (2022)

Clearance of circulating IgA immune complexes is mediated by a specific receptor on Kupffer cells in mice
Publicado: (1984)

Nucleation of platelets with bloodborne pathogens on Kupffer cell precedes other innate immunity and contributes to bacterial clearance
por: Wong, Connie H. Y., et al.
Publicado: (2013)

Differences in phagocytosis by polymorphonuclear leucocytes (PMNs) and monocytes (Mos) in endotoxemia and endotoxin (ET) tolerance
por: Staubach, K-H, et al.
Publicado: (2000)

Intestinal Metabolites Influence Macrophage Phagocytosis and Clearance of Bacterial Infection
por: O’Callaghan, Amy A., et al.
Publicado: (2021)

Intravital imaging reveals improved Kupffer cell-mediated phagocytosis as a mode of action of glycoengineered anti-CD20 antibodies
por: Grandjean, Capucine L., et al.
Publicado: (2016)

Kupffer cells in hepatotoxicity
por: Hassan, Reham
Publicado: (2020)

INDUCTION OF MACROPHAGE PLASMINOGEN ACTIVATOR BY ENDOTOXIN STIMULATION AND PHAGOCYTOSIS : Evidence for A Two-Stage Process
por: Gordon, Saimon, et al.
Publicado: (1974)

Chronic Ethanol Feeding Modulates Inflammatory Mediators, Activation of Nuclear Factor-κB, and Responsiveness to Endotoxin in Murine Kupffer Cells and Circulating Leukocytes
por: Maraslioglu, Miriam, et al.
Publicado: (2014)

Effect of Kupffer cells depletion on ABC phenomenon induced by Kupffer cells-targeted liposomes
por: Lai, Chaoyang, et al.
Publicado: (2019)

The role of full-length apoE in clearance of Gram-negative bacteria and their endotoxins
por: Petruk, Ganna, et al.
Publicado: (2021)

ApoM binds endotoxin contributing to neutralization and clearance by High Density Lipoprotein
por: Mousa, Hanaa, et al.
Publicado: (2023)

Toll-like receptor 4 in phagocytosis of Escherichia coli by endotoxin-activated human neutrophils in whole blood
por: Prokhorenko, I, et al.
Publicado: (2012)

Kupffer Cells in Health and Disease
por: Woltman, Andrea M., et al.
Publicado: (2014)

Phagocytosis is a primary determinant of pulmonary clearance of clinical Klebsiella pneumoniae isolates
por: van der Geest, Rick, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_7v0eovr8gpb3nn5v5svgjnvd18