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Effect of etoposide-induced alteration of the Mdm2-Rb signaling pathway on cellular senescence in A549 lung adenocarcinoma cells

The present study aimed to investigate the effect of various concentrations of etoposide (VP-16) on the E3 ubiquitin-protein ligase Mdm2 (Mdm2)-retinoblastoma (Rb) signaling pathway in the cellular senescence of A549 lung adenocarcinoma cells. A549 cells were randomly divided into the following four...

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Detalles Bibliográficos
Autores principales:	Dai, Wenjing, Jiang, Yi, Chen, Kairong, Qiu, Jing, Sun, Jian, Zhang, Wei, Zhou, Xiafei, Huang, Na, Li, Yunhui, Li, Wancheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607649/ https://www.ncbi.nlm.nih.gov/pubmed/28959361 http://dx.doi.org/10.3892/ol.2017.6684

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