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LINGO-1 and AMIGO3, potential therapeutic targets for neurological and dysmyelinating disorders?
Leucine rich repeat proteins have gained considerable interest as therapeutic targets due to their expression and biological activity within the central nervous system. LINGO-1 has received particular attention since it inhibits axonal regeneration after spinal cord injury in a RhoA dependent manner...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Medknow Publications & Media Pvt Ltd
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607814/ https://www.ncbi.nlm.nih.gov/pubmed/28966634 http://dx.doi.org/10.4103/1673-5374.213538 |