Cargando…
ERβ and ApoE isoforms interact to regulate BDNF–5-HT(2A) signaling and synaptic function in the female brain
BACKGROUND: Depression has been reported to be commonly manifested in patients with Alzheimer’s disease (AD) and is considered a risk factor for AD. The human apolipoprotein E (ApoE) gene exists in three major isoforms (coded by ε2, ε3, and ε4), and the ε4 allele has been associated with a greater i...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607839/ https://www.ncbi.nlm.nih.gov/pubmed/28934977 http://dx.doi.org/10.1186/s13195-017-0305-3 |