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Generation of Prostate Cancer Cell Models of Resistance to the Anti-mitotic Agent Docetaxel

Microtubule targeting agents (MTAs) are a mainstay in the treatment of a wide range of tumors. However, acquired resistance to chemotherapeutic drugs is a common mechanism of disease progression and a prognostic-determinant feature of malignant tumors. In prostate cancer (PC), resistance to MTAs suc...

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Detalles Bibliográficos
Autores principales: Mohr, Lisa, Carceles-Cordon, Marc, Woo, Jungreem, Cordon-Cardo, Carlos, Domingo-Domenech, Josep, Rodriguez-Bravo, Veronica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607877/
https://www.ncbi.nlm.nih.gov/pubmed/28930981
http://dx.doi.org/10.3791/56327