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Engineering microbial physiology with synthetic polymers: cationic polymers induce biofilm formation in Vibrio cholerae and downregulate the expression of virulence genes
Here we report the first application of non-bactericidal synthetic polymers to modulate the physiology of a bacterial pathogen. Poly(N-[3-(dimethylamino)propyl] methacrylamide) (P1) and poly(N-(3-aminopropyl)methacrylamide) (P2), cationic polymers that bind to the surface of V. cholerae, the infecti...
Autores principales: | Perez-Soto, Nicolas, Moule, Lauren, Crisan, Daniel N., Insua, Ignacio, Taylor-Smith, Leanne M., Voelz, Kerstin, Fernandez-Trillo, Francisco, Krachler, Anne Marie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607900/ https://www.ncbi.nlm.nih.gov/pubmed/28970909 http://dx.doi.org/10.1039/c7sc00615b |
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