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Periaortic lymphoma in a cat

CASE SUMMARY: A 14-year-old neutered male Siamese cat was presented with a 3 month history of lethargy, inappetence, dehydration, hindlimb ataxia and intermittent proprioceptive deficits in the hindlimbs. Physical examination revealed low body condition score (1.75/5), pallor and bilateral basilar g...

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Autores principales: Bree, Laura, Bergamino, Chiara, Mullins, Ronan, Kelly, Pamela, Shiel, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607923/
https://www.ncbi.nlm.nih.gov/pubmed/28955476
http://dx.doi.org/10.1177/2055116917729627
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author Bree, Laura
Bergamino, Chiara
Mullins, Ronan
Kelly, Pamela
Shiel, Robert
author_facet Bree, Laura
Bergamino, Chiara
Mullins, Ronan
Kelly, Pamela
Shiel, Robert
author_sort Bree, Laura
collection PubMed
description CASE SUMMARY: A 14-year-old neutered male Siamese cat was presented with a 3 month history of lethargy, inappetence, dehydration, hindlimb ataxia and intermittent proprioceptive deficits in the hindlimbs. Physical examination revealed low body condition score (1.75/5), pallor and bilateral basilar grade II/VI systolic heart murmur. Neurological examination revealed hindlimb ataxia, severe atrophy of the hindlimb musculature, intermittent hindlimb proprioceptive deficits and normoreflexia. Clinicopathological investigations revealed non-regenerative anaemia (haematocrit 0.17 l/l; reference interval [RI] 0.24–0.45 l/l) and increased feline pancreatic lipase concentration (Spec fPL test [IDEXX] 8.3 μg/l; RI 0.1–3.5 μg/l). Feline leukaemia virus antigen and feline immunodeficiency virus antibody tests were negative. Thoracic and abdominal imaging revealed a soft tissue structure in the area of the thoracoabdominal aorta. CT confirmed a periaortic contrast-enhancing mass extending from the level of T9–L2, with associated intervertebral infiltration at the level of T11–T12. Post-mortem examination confirmed the presence of a solid, white, multinodular, well-demarcated mass encircling the aorta extending from T9–L2. Based on histopathology and immunohistochemistry, a diagnosis of B-cell lymphoma was made. Lymphoma was also identified histopathologically within the kidneys and spleen. Evidence of mild Wallerian degeneration was present within the spinal cord, indicating compression at the level of the periaortic mass. RELEVANCE AND NOVEL INFORMATION: To our knowledge, this is the first report of periaortic lymphoma in the cat. Although periaortic tumours are exceptionally rare in veterinary medicine, lymphoma should be considered as a differential in cats.
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spelling pubmed-56079232017-09-27 Periaortic lymphoma in a cat Bree, Laura Bergamino, Chiara Mullins, Ronan Kelly, Pamela Shiel, Robert JFMS Open Rep Case Report CASE SUMMARY: A 14-year-old neutered male Siamese cat was presented with a 3 month history of lethargy, inappetence, dehydration, hindlimb ataxia and intermittent proprioceptive deficits in the hindlimbs. Physical examination revealed low body condition score (1.75/5), pallor and bilateral basilar grade II/VI systolic heart murmur. Neurological examination revealed hindlimb ataxia, severe atrophy of the hindlimb musculature, intermittent hindlimb proprioceptive deficits and normoreflexia. Clinicopathological investigations revealed non-regenerative anaemia (haematocrit 0.17 l/l; reference interval [RI] 0.24–0.45 l/l) and increased feline pancreatic lipase concentration (Spec fPL test [IDEXX] 8.3 μg/l; RI 0.1–3.5 μg/l). Feline leukaemia virus antigen and feline immunodeficiency virus antibody tests were negative. Thoracic and abdominal imaging revealed a soft tissue structure in the area of the thoracoabdominal aorta. CT confirmed a periaortic contrast-enhancing mass extending from the level of T9–L2, with associated intervertebral infiltration at the level of T11–T12. Post-mortem examination confirmed the presence of a solid, white, multinodular, well-demarcated mass encircling the aorta extending from T9–L2. Based on histopathology and immunohistochemistry, a diagnosis of B-cell lymphoma was made. Lymphoma was also identified histopathologically within the kidneys and spleen. Evidence of mild Wallerian degeneration was present within the spinal cord, indicating compression at the level of the periaortic mass. RELEVANCE AND NOVEL INFORMATION: To our knowledge, this is the first report of periaortic lymphoma in the cat. Although periaortic tumours are exceptionally rare in veterinary medicine, lymphoma should be considered as a differential in cats. SAGE Publications 2017-09-18 /pmc/articles/PMC5607923/ /pubmed/28955476 http://dx.doi.org/10.1177/2055116917729627 Text en © The Author(s) 2017 http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages(https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Bree, Laura
Bergamino, Chiara
Mullins, Ronan
Kelly, Pamela
Shiel, Robert
Periaortic lymphoma in a cat
title Periaortic lymphoma in a cat
title_full Periaortic lymphoma in a cat
title_fullStr Periaortic lymphoma in a cat
title_full_unstemmed Periaortic lymphoma in a cat
title_short Periaortic lymphoma in a cat
title_sort periaortic lymphoma in a cat
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607923/
https://www.ncbi.nlm.nih.gov/pubmed/28955476
http://dx.doi.org/10.1177/2055116917729627
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AT shielrobert periaorticlymphomainacat