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Wearable technology to reduce sedentary behavior and CVD risk in older adults: Design of a randomized controlled trial
Persons aged over 65 years account for over the vast majority of healthcare expenditures and deaths attributable to cardiovascular disease (CVD). Accordingly, reducing CVD risk among older adults is an important public health priority. Structured physical activity (i.e. exercise) is a well-documente...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608105/ https://www.ncbi.nlm.nih.gov/pubmed/28944304 http://dx.doi.org/10.1016/j.conctc.2017.04.003 |
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author | Krehbiel, Lisa M. Layne, Andrew S. Sandesara, Bhanuprasad Manini, Todd M. Anton, Stephen D. Buford, Thomas W. |
author_facet | Krehbiel, Lisa M. Layne, Andrew S. Sandesara, Bhanuprasad Manini, Todd M. Anton, Stephen D. Buford, Thomas W. |
author_sort | Krehbiel, Lisa M. |
collection | PubMed |
description | Persons aged over 65 years account for over the vast majority of healthcare expenditures and deaths attributable to cardiovascular disease (CVD). Accordingly, reducing CVD risk among older adults is an important public health priority. Structured physical activity (i.e. exercise) is a well-documented method of decreasing CVD risk, but recent large-scale trials suggest that exercise alone is insufficient to reduce CVD events in high-risk populations of older adults. Thus adjuvant strategies appear necessary to reduce CVD risk. Accumulating evidence indicates that prolonged sedentary behavior (e.g. sitting) has detrimental health effects that are independent of engagement in recommended levels of moderate-intensity exercise. Yet clinical trials in this area are lacking. We hypothesize that exercise, when combined with a novel technology based intervention specifically designed to reduce sedentary behavior will reduce CVD risk among sedentary older adults. The purpose of this study is to evaluate the feasibility and efficacy of combining a traditional, structured exercise intervention with an innovative intervention designed to decrease sedentary behavior and increase non-exercise physical activity (NEPA). This study will provide us with critical data necessary to design and implement a full-scale trial to test our central hypothesis. Participants aged ≥60 years with moderate to high risk of coronary heart disease (CHD) events are randomly assigned to either the exercise and technology intervention (EX + NEPA) or exercise alone (EX) groups. Study dependent outcomes include changes in 1) daily activity patterns, 2) blood pressure, 3) exercise capacity, 4) waist circumference, and 5) circulating indices of cardiovascular function. This study will provide critical information for designing a fully-powered clinical trial, which could have health implications for the ever increasing population of older adults. |
format | Online Article Text |
id | pubmed-5608105 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-56081052018-05-08 Wearable technology to reduce sedentary behavior and CVD risk in older adults: Design of a randomized controlled trial Krehbiel, Lisa M. Layne, Andrew S. Sandesara, Bhanuprasad Manini, Todd M. Anton, Stephen D. Buford, Thomas W. Contemp Clin Trials Commun Article Persons aged over 65 years account for over the vast majority of healthcare expenditures and deaths attributable to cardiovascular disease (CVD). Accordingly, reducing CVD risk among older adults is an important public health priority. Structured physical activity (i.e. exercise) is a well-documented method of decreasing CVD risk, but recent large-scale trials suggest that exercise alone is insufficient to reduce CVD events in high-risk populations of older adults. Thus adjuvant strategies appear necessary to reduce CVD risk. Accumulating evidence indicates that prolonged sedentary behavior (e.g. sitting) has detrimental health effects that are independent of engagement in recommended levels of moderate-intensity exercise. Yet clinical trials in this area are lacking. We hypothesize that exercise, when combined with a novel technology based intervention specifically designed to reduce sedentary behavior will reduce CVD risk among sedentary older adults. The purpose of this study is to evaluate the feasibility and efficacy of combining a traditional, structured exercise intervention with an innovative intervention designed to decrease sedentary behavior and increase non-exercise physical activity (NEPA). This study will provide us with critical data necessary to design and implement a full-scale trial to test our central hypothesis. Participants aged ≥60 years with moderate to high risk of coronary heart disease (CHD) events are randomly assigned to either the exercise and technology intervention (EX + NEPA) or exercise alone (EX) groups. Study dependent outcomes include changes in 1) daily activity patterns, 2) blood pressure, 3) exercise capacity, 4) waist circumference, and 5) circulating indices of cardiovascular function. This study will provide critical information for designing a fully-powered clinical trial, which could have health implications for the ever increasing population of older adults. Elsevier 2017-04-20 /pmc/articles/PMC5608105/ /pubmed/28944304 http://dx.doi.org/10.1016/j.conctc.2017.04.003 Text en © 2017 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Article Krehbiel, Lisa M. Layne, Andrew S. Sandesara, Bhanuprasad Manini, Todd M. Anton, Stephen D. Buford, Thomas W. Wearable technology to reduce sedentary behavior and CVD risk in older adults: Design of a randomized controlled trial |
title | Wearable technology to reduce sedentary behavior and CVD risk in older adults: Design of a randomized controlled trial |
title_full | Wearable technology to reduce sedentary behavior and CVD risk in older adults: Design of a randomized controlled trial |
title_fullStr | Wearable technology to reduce sedentary behavior and CVD risk in older adults: Design of a randomized controlled trial |
title_full_unstemmed | Wearable technology to reduce sedentary behavior and CVD risk in older adults: Design of a randomized controlled trial |
title_short | Wearable technology to reduce sedentary behavior and CVD risk in older adults: Design of a randomized controlled trial |
title_sort | wearable technology to reduce sedentary behavior and cvd risk in older adults: design of a randomized controlled trial |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608105/ https://www.ncbi.nlm.nih.gov/pubmed/28944304 http://dx.doi.org/10.1016/j.conctc.2017.04.003 |
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