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Angiomyolipoma of the Adrenal Gland: A Report of Two Cases and Review of the Literature

Case series Patient: Male, 36 • Female, 61 Final Diagnosis: Adrenal angiomyolipoma Symptoms: Asymptomatic Medication: — Clinical Procedure: — Specialty: Radiology OBJECTIVE: Rare disease BACKGROUND: Angiomyolipoma is a benign tumor composed of blood vessels, smooth muscle cells, and adipose tissue a...

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Autores principales: Ghimire, Obin, Wenzheng, Li, Huaping, Liu, Wenguang, Liu, Yigang, Pei, Jiale, Hou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608147/
https://www.ncbi.nlm.nih.gov/pubmed/28904331
http://dx.doi.org/10.12659/AJCR.903908
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author Ghimire, Obin
Wenzheng, Li
Huaping, Liu
Wenguang, Liu
Yigang, Pei
Jiale, Hou
author_facet Ghimire, Obin
Wenzheng, Li
Huaping, Liu
Wenguang, Liu
Yigang, Pei
Jiale, Hou
author_sort Ghimire, Obin
collection PubMed
description Case series Patient: Male, 36 • Female, 61 Final Diagnosis: Adrenal angiomyolipoma Symptoms: Asymptomatic Medication: — Clinical Procedure: — Specialty: Radiology OBJECTIVE: Rare disease BACKGROUND: Angiomyolipoma is a benign tumor composed of blood vessels, smooth muscle cells, and adipose tissue and has been described as belonging to the group of tumors of perivascular epithelioid cell origin (PEComa), commonly found in the kidneys and strongly associated with tuberous sclerosis. Only a few cases of extra-renal angiomyolipoma have previously been reported in the literature, most commonly in the liver. Adrenal angiomyolipoma is very rare, is usually asymptomatic, and is often found incidentally, with only 14 previously reported cases identified in the literature. CASE REPORTS: We report two cases of adrenal angiomyolipoma that were identified by abdominal computed tomography (CT). The first case presented in a 36-year-old man and was an oval-shaped adrenal mass, measuring 5.2×4.2×3.1 cm. The second case presented in a 61-year-old woman and was a round-shaped mass measuring 8.6×9.5×8.1 cm. Both patients underwent adrenalectomy. Histopathology and immunohistochemistry confirmed the diagnosis of benign angiomyolipoma composed of adipose tissues, blood vessels, and smooth muscle cells. CONCLUSIONS: We present two rare cases of adrenal angiomyolipoma. We have reviewed the literature and identified 14 other cases of adrenal angiomyolipoma, and discuss the clinical, radiological, and pathological features of this rare tumor.
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spelling pubmed-56081472017-09-27 Angiomyolipoma of the Adrenal Gland: A Report of Two Cases and Review of the Literature Ghimire, Obin Wenzheng, Li Huaping, Liu Wenguang, Liu Yigang, Pei Jiale, Hou Am J Case Rep Articles Case series Patient: Male, 36 • Female, 61 Final Diagnosis: Adrenal angiomyolipoma Symptoms: Asymptomatic Medication: — Clinical Procedure: — Specialty: Radiology OBJECTIVE: Rare disease BACKGROUND: Angiomyolipoma is a benign tumor composed of blood vessels, smooth muscle cells, and adipose tissue and has been described as belonging to the group of tumors of perivascular epithelioid cell origin (PEComa), commonly found in the kidneys and strongly associated with tuberous sclerosis. Only a few cases of extra-renal angiomyolipoma have previously been reported in the literature, most commonly in the liver. Adrenal angiomyolipoma is very rare, is usually asymptomatic, and is often found incidentally, with only 14 previously reported cases identified in the literature. CASE REPORTS: We report two cases of adrenal angiomyolipoma that were identified by abdominal computed tomography (CT). The first case presented in a 36-year-old man and was an oval-shaped adrenal mass, measuring 5.2×4.2×3.1 cm. The second case presented in a 61-year-old woman and was a round-shaped mass measuring 8.6×9.5×8.1 cm. Both patients underwent adrenalectomy. Histopathology and immunohistochemistry confirmed the diagnosis of benign angiomyolipoma composed of adipose tissues, blood vessels, and smooth muscle cells. CONCLUSIONS: We present two rare cases of adrenal angiomyolipoma. We have reviewed the literature and identified 14 other cases of adrenal angiomyolipoma, and discuss the clinical, radiological, and pathological features of this rare tumor. International Scientific Literature, Inc. 2017-09-14 /pmc/articles/PMC5608147/ /pubmed/28904331 http://dx.doi.org/10.12659/AJCR.903908 Text en © Am J Case Rep, 2017 This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) )
spellingShingle Articles
Ghimire, Obin
Wenzheng, Li
Huaping, Liu
Wenguang, Liu
Yigang, Pei
Jiale, Hou
Angiomyolipoma of the Adrenal Gland: A Report of Two Cases and Review of the Literature
title Angiomyolipoma of the Adrenal Gland: A Report of Two Cases and Review of the Literature
title_full Angiomyolipoma of the Adrenal Gland: A Report of Two Cases and Review of the Literature
title_fullStr Angiomyolipoma of the Adrenal Gland: A Report of Two Cases and Review of the Literature
title_full_unstemmed Angiomyolipoma of the Adrenal Gland: A Report of Two Cases and Review of the Literature
title_short Angiomyolipoma of the Adrenal Gland: A Report of Two Cases and Review of the Literature
title_sort angiomyolipoma of the adrenal gland: a report of two cases and review of the literature
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608147/
https://www.ncbi.nlm.nih.gov/pubmed/28904331
http://dx.doi.org/10.12659/AJCR.903908
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