Cargando…

Automated Radiochemical Synthesis of [(18)F]3F4AP: A Novel PET Tracer for Imaging Demyelinating Diseases

3-[(18)F]fluoro-4-aminopyridine, [(18)F]3F4AP, is a radiofluorinated analog of the FDA-approved drug for multiple sclerosis 4-aminopyridine (4AP). This compound is currently under investigation as a PET tracer for demyelination. We recently described a novel chemical reaction to produce metafluorina...

Descripción completa

Detalles Bibliográficos
Autores principales: Brugarolas, Pedro, Bhuiyan, Mohammed, Kucharski, Anna, Freifelder, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MyJove Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608160/
https://www.ncbi.nlm.nih.gov/pubmed/28605366
http://dx.doi.org/10.3791/55537