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Automated Radiochemical Synthesis of [(18)F]3F4AP: A Novel PET Tracer for Imaging Demyelinating Diseases

3-[(18)F]fluoro-4-aminopyridine, [(18)F]3F4AP, is a radiofluorinated analog of the FDA-approved drug for multiple sclerosis 4-aminopyridine (4AP). This compound is currently under investigation as a PET tracer for demyelination. We recently described a novel chemical reaction to produce metafluorina...

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Detalles Bibliográficos
Autores principales:	Brugarolas, Pedro, Bhuiyan, Mohammed, Kucharski, Anna, Freifelder, Richard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MyJove Corporation 2017
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608160/ https://www.ncbi.nlm.nih.gov/pubmed/28605366 http://dx.doi.org/10.3791/55537

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