Cargando…

Stage specific requirement of platelet-derived growth factor receptor-α in embryonic development

BACKGROUND: Platelet-derived growth factor receptor alpha (PDGFRα) is a cell-surface receptor tyrosine kinase for platelet-derived growth factors. Correct timing and level of Pdgfra expression is crucial for embryo development, and deletion of Pdgfra caused developmental defects of multiple endoderm...

Descripción completa

Detalles Bibliográficos
Autores principales: Qian, Chen, Wong, Carol Wing Yan, Wu, Zhongluan, He, Qiuming, Xia, Huimin, Tam, Paul Kwong Hang, Wong, Kenneth Kak Yuen, Lui, Vincent Chi Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608218/
https://www.ncbi.nlm.nih.gov/pubmed/28934221
http://dx.doi.org/10.1371/journal.pone.0184473